The Patents below are a small, but significant subset of all those filed and approved.
Please see Dr. Albert Kausch’s CV for a more complete list. All links lead to additional, online abstracts and US Patent and Trademark Office (USPTO) listings.
1985. Chimaeric gene coding for a transit peptide and a heterologous polypeptide.
This patent enabled delivery of transgenic proteins to the chloroplast for targeted traits including RoundUp Ready and Bt Technologies (both chloroplast traits) grown over millions of hectares worldwide. These transgenic crops all utilize a transit peptide to target the protein!
1996. Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof.
These were the first fertile GMO corn plants! Kausch made the cell cultures and the Kausch Lab was the tissue and cell culture group. The embryogenic suspension cultures SC82 and SC716 were made in the Kausch Lab.
1996. Isolation of biological materials using magnetic particles.
Magnet nanoparticle separation of biological materials as a broad patent for a novel technology. This patent formed the basis for commercial magnetic bead (Dynal) high-throughput DNA sequencing (HySeq).
1996. Process of producing fertile transgenic zea mays plants and progeny comprising a gene encoding phosphinothricin acetyl transferase.
This patent protected the first herbicide resistant corn plants. As a broad patent, this concept was further reiterated as a technology across most cereal crops.
1998. Transgenic maize with increased mannitol content.
Ultimately, and not intuitive, this process is not very effective for induce drought tolerance in maze, but this patent teaches how to produce large amounts of osmoticum in plants.
1998. Chimaeric gene coding for a transit peptide and a heterologous polypeptide
This patent capture using the transit peptide to make transgenic plants with inherited chloroplastic traits. (See earlier patented and published work).
2000. Chimaeric gene coding for a transit peptide and a heterologous peptide.
This patent covers delivery of a foreign protein to chloroplasts using the transit peptide technology for construction chimeric genes for protein fusions.
2000. Method for reduction of transgene copy number.
This is a transformation biology patent designed to limit the number of inserted transgenes in an event. Control of copy number integration would remain an issue for microprojectile bombardment created transgenic events.
2002. Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof.
This is a body of intellectual property related to processes optimized for transformation of corn, which was deployed for commercial production of the first genetically engineered corn introduced in the United States.
2004. Green Garlic and Methods of Production.
This is a patent on Green Garlic as a new vegetable! I invented a new vegetable! By simple and rigorous varietal selection methods.
2007. Green Garlic and Methods of Production.
The unique methods for the large-scale growing conditions of green garlic as a new vegetable for commercial production.
2010. Prevention of transgene escape in genetically modified perennial plants.
This patent teaches various molecular strategies for gene confinement and hybrid plant systems. Dr. Kausch has eight years research experience with plant gene containment strategies.
2010. Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof.
Improvements to transformation methods for corn with demonstration of the introduction of several commercially significant trait genes.
2011. Green Garlic and Methods of Production.
Improved methods for varietal selection for improved green garlic germplasm. There are over 112 new varieties that have yet to apply for Plant Variety Protection (PVP).
2016. Transgene and mutational control of sexuality in maize and related grasses.
Maize is a monecious plant with the male flower, the tassel terminal and the female flower on its axis. The maize flower initiates as a perfect flower, where the female pistilate primordia are aborted in the male and the male staminate parts are aborted in the ear primordia. This patent shows use of the female sexuality in maize for hybrid plants systems generally.